Major Employers
| Name | Type | Employees |
|---|---|---|
| Federal Government | Government | 20846 |
| Children's Mercy Hospital | Healthcare | 8382 |
| Saint Luke's Health System | Health care | 5055 |
| Honeywell Manufacturing | Electronic & mech. weapons components mfg. | 5000 |
| Internal Revenue Service | Government | 4600 |
| City of Kansas City, MO | Government | 4411 |
| Truman Medical Center, Inc. | Health services | 4232 |
| Burns & McDonnell | Architect/Engineering | 2907 |
| University of Missouri-KC | Higher education | 2427 |
| Commerce Bank | Banking | 2409 |
| Hallmark Cards, Inc. | Greeting cards | 2262 |
| Homeland Security - USCIS | Federal government | 2200 |
| JE Dunn Construction | Construction | 1800 |
| H & R Block, Inc. | Tax prep & financial services | 1750 |
| Olin Winchester, Lake City Ammunition Plant | Ammunition | 1750 |
| UMB Financial Corp. | Banking | 1706 |
| GEHA | Medical insurance service center | 1430 |
| Centerpoint Medical Center | Healthcare | 1416 |
| Blue Cross/Blue Shield of Kansas City | Insurance | 1300 |
| Lockton Companies | Insurance | 1286 |
| State Street | Mutual fund & insurance industry services | 1222 |
| American Century Investments, Inc. | Mutual funds | 1103 |
| Carondelet Health | Health services | 1068 |
| Spectrum | Cable television | 800 |
| Shook Hardy & Bacon | Law firm | 712 |
| Evergy | Electrical utility | 671 |
| Viracor Eurofins | Clinical and diagnostic testing | 594 |
| Bayer CropScience, Core Technologies Center | Crop protection products | 500 |
| Peterson Manufacturing Company | Transportation equipment mfg. | 490 |
| HNTB Corp. | Architects/Engineers | 480 |
| Fike Corporation | Manufacturer of process and life safety products | 471 |
| CVS Health | Pharmaceutical services | 450 |
| Kansas City Life Insurance Co. | Insurance | 437 |
| Silgan Dispensing Systems Corporation | Spray trigger mechanisms mfg. | 420 |
| Alstom Signaling Operation, LLC | Railroad signaling systems | 400 |
| Clarkson Construction Company | Construction | 400 |
| Quest Diagnostics | Pharmaceutical customer service | 350 |
| Owner Operator & Independent Drivers Association | Professional association | 327 |