Major Employers
| Name | Type | Employees |
|---|---|---|
| Osawatomie State Hospital | Mental healthcare | 366 |
| Osawatomie School District | Education | 197 |
| Tri-Ko, Inc. | Social Services | 95 |
| First Option Bank | Bank | 72 |
| Life Care Center of Osawatomie | Healthcare | 67 |
| City of Osawatomie | Government | 50 |